iStent Inject for Glaucoma

iStent Inject

iStent Injects are a type of Minimally Invasive Glaucoma Surgery (MIGS). Following implantation, they lower the IOP by increasing drainage of the intraocular fluid (aqueous humour) through the implants hence reducing the eye pressure. They have shown promising results in the short-to-medium term, and have a higher safety profile and faster recovery time than conventional glaucoma surgeries, as there is minimal tissue disruption.

As there is less IOP reduction compared to conventional glaucoma surgeries, these procedures are targeted at patients with mild to moderate glaucoma. They can be performed together with cataract surgery, or as a stand-alone procedure. Hence, this is a good option to consider for patients with cataracts and early to moderate glaucoma, as it can potentially reduce the number of glaucoma medications after surgery. When performed at the same time as cataract surgery, there are no additional cuts or wounds, hence patients can expect the same recovery time as cataract surgery alone. 

The iStent was the first MIGS device to be FDA-approved, and the iStent Inject is a newer device with a modified injector that can be simultaneously loaded with 2 stents (Figure 1). Each titanium stent measures 0.36 by 0.23 millimetres and it is the smallest medical device known to be implanted in the human body (Figure 2). The stents are inserted into the drainage canals to allow increased outflow of fluid from the eye (Figure 3).


Figure 1. iStent inject stents and the iStent inject trabecular micro-bypass stent system

APEC Asia Pacific Eye Centre Glaucoma iStent Inject 2 Glaukos Penny

Figure 2. The iStent inject stents, being the smallest medical device known to be implanted in the human body.

Glaucoma iStent Inject Process Animation

Restores Natural Outflow Pathway

When implanted, the iStent inject® creates two patent bypass pathways through the trabecular meshwork — the main source of resistance for aqueous outflow—resulting in multi-directional flow through Schlemm’s canal. 

Is The iStent Inject Effective?

A prospective multicentre study has found that following implantation of 2 iStent Injects, majority of the patients (86.9%) achieved a reduction in the number of glaucoma medications. There were few to no adverse events reported following implantation of the iStent Inject. In fact, a combined cataract surgery with iStent Injects has a safety profile similar to cataract surgery alone.

Figure 3. The iStent inject in the drainage canal (trabecular meshwork).

Our Glaucoma Specialist - Dr Tan Yar Li

  • 10+ Years of Experience
  • Former Consultant at Singapore National Eye Centre (SNEC)
  • Former Deputy Head of the Department of Ophthalmology at Changi General Hospital
  • Awarded 3 gold medals for Best Candidate in Glaucoma, Vitreoretinal as well as Neuro-ophthalmology in the Eye Specialists’ Exit exam
  • One of the first few surgeons in Singapore to perform Minimally Invasive Glaucoma Surgery (MIGS)
Dr Tan has more than 10 years of ophthalmology experience and her current clinical practice includes general ophthalmology and cataract surgery, as well as in the subspeciality field of Glaucoma. Her current area of interest is in Minimally Invasive Glaucoma Surgery (MIGS) and she was also one of the first few surgeons in Singapore to perform the surgeries.
Dr Tan Yar Li with Patient Glaucoma Specialist

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APEC’s reputation is one that has been built around experience and trust, as evidenced by our large pool of referral patients.

Glaucoma Screening & Testing (subject to 9% GST)

Glaucoma Screening – $80

  • Visual Acuity/Auto-Refraction
  • Eye Pressure Check (Tonometry)
  • Corneal Thickness Measurement
  • Optic Nerve Scan/Optical Coherence Tomography (Nerve)
  • Optic Disc Photography
  • Doctor’s Report

Cataract/Glaucoma/Age-Related Macular Degeneration Screening – $200
( Inclusive of Consultation with Doctor )

  • Visual Acuity/Refraction
  • Eye Pressure Check (Tonometry)
  • Corneal Thickness Measurement
  • Optic Nerve & Macular Scan/Optical Coherence Tomography (Nerve & Macular)
  • Optic Nerve & Retinal Photography
  • Doctor’s Consult